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Cat. No.: HY-N12243

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Kopsininic acid

Kopsininic acid is a natural product derived from Kopsia hainanensis. Kopsininic acid can be used in the research of rheumatoid arthritis, pharyngitis, tonsillitis and edema.

For research use only. We do not sell to patients.

CAS No.: 7222-19-7
Formula: C₂₀H₂₄N₂O₂
Molecular Weight:324.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Kopsininic acid Chemical Structure

CAS No.: 7222-19-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Kopsininic acid is a natural product derived from Kopsia hainanensis. Kopsininic acid can be used in the research of rheumatoid arthritis, pharyngitis, tonsillitis and edema^[1].

Chemical Information

CAS No. 7222-19-7
Molecular Weight 324.42
Formula C₂₀H₂₄N₂O₂
SMILES

O=C([C@@H]1C[C@@]23CCCN4CC[C@]5([C@@]43[H])C6=C(N[C@]15CC2)C=CC=C6)O
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Collagen-Induced Arthritis
Collagen-induced arthritis (CIA) is an autoimmune murine model of rheumatoid arthritis in which immunization with type II collagen (CII) emulsified in an adjuvant induces a T cell- and autoantibody-driven inflammatory arthritis characterized by synovial hyperplasia, immune cell infiltration, and joint destruction. The model typically relies on genetically susceptible mouse strains (e. g. , DBA/1) and reproduces key features of human rheumatoid arthritis, including anti-collagen immune responses and progressive joint inflammation. Disease onset generally occurs within ~3-4 weeks after immunization, depending on antigen/adjuvant combinations and protocol variation. The immunopathology is driven by adaptive immune activation against CII, leading to systemic and local joint inflammation mediated by pro-inflammatory cytokines and effector immune cells, making CIA a standard preclinical platform for evaluating immunomodulatory and anti-arthritic interventions.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hop NQ, et al. A comprehensive review on phytochemistry and pharmacology of genus Kopsia: monoterpene alkaloids - major secondary metabolites. RSC Adv. 2022 Jul 5;12(30):19171-19208.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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