Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
Urease
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "Urease" in MCE Product Catalog:
Cat. No.: HY-W019724R
CAS No.: 563-96-2
Cat. No.: HY-W207687
CAS No.: 4506-62-1
Target:
Research Areas:
Thymidine phosphorylase-IN-1 (compound C17) is a potent Thymidine phosphorylase inhibitor with an IC50 of 3.24 μM. Thymidine phosphorylase-IN-1 exhibits high binding affinity for Urease and Xanthine oxidase, with Kd values of 0.02 and 0.15 μM, respectively. Thymidine phosphorylase-IN-1 achieves optimal geometric complementarity and stable binding with the catalytic site of the target enzyme through hydrogen bonding, hydrophobic interactions, and π-π stacking mediated by the aminophenyl nitrogen atom. Thymidine phosphorylase-IN-1 can be used for research on tuberculosis .
Cat. No.: HY-187201
Target:
Research Areas:
Antimicrobial agent-54 is a ciprofloxacin-derived multi-target antimicrobial agent that inhibits E. coli DNA gyrase, S. aureus topoisomerase IV, LpxC and urease with IC50 values of 0.182, 3.501, 0.052 and 6.254 μM, respectively. The MIC of Antimicrobial agent-54 against E. coli ATCC 8739 is 0.20 μM. Antimicrobial agent-54 interferes with bacterial cell division, causes transient membrane disruption in Gram-positive bacteria, and induces aberrant penicillin-binding protein activity in Gram-negative bacteria. Antimicrobial agent-54 can be used in the research of bacterial infections, including multidrug-resistant bacterial infections and mycobacterial infections .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
