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Cat. No.: HY-100292

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SL910102

SL910102 is a nonpeptide angiotensin AT₁ receptor antagonist.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 144756-71-8
화학식: C₃₀H₃₀N₆O
분자량:490.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

SL910102 Chemical Structure

CAS No.: 144756-71-8

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocol
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

SL910102 is a nonpeptide angiotensin AT₁ receptor antagonist.

IC₅₀ & Target

AT1 Receptor

All Angiotensin Receptor Isoforms :

In Vitro

SL910102 (SL 91.0102-90 DL) is a unlabelled nonpeptide AT₁-antagonist, which is tested for its ability to compete with [¹²⁵J](Sar¹-Ile⁸)-angiotensin II for specific AT₁-receptor sites in rat lung homogenate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 144756-71-8
분자량 490.60
화학식 C₃₀H₃₀N₆O
SMILES

O=C1N=C(CCC2=CC=CC=C2)NC(CCCC)=C1CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

Kinase Assay^[1]

For saturation as well as displacement studies, rat lung homogenate is incubated in either Hepes-buffer or blank human or rat plasma yielding 50 μg protein per well in a total assay volume of 300 μL. To ensure equilibrium conditions (see binding kinetics), the samples are maintained for 60 min at 25°C under continuous rotation. All experiments are carried out in duplicate, and the results are confirmed with n=3-5 replicates over the following days^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Soldner A, et al. A radioreceptor assay for the analysis of AT1-receptor antagonists. Correlation with complementary LC data reveals a potential contribution of active metabolites. J Pharm Biomed Anal. 1998 May;17(1):111-24. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocol
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

SL910102

Losartan

Valsartan

Candesartan

Olmesartan

AVE 0991

Olmesartan medoxomil

Azilsartan

CGP-42112

Olmesartan medoxomil (Standard)

Azilsartan medoxomil

PD 123319 ditrifluoroacetate

Eprosartan mesylate

All Angiotensin Receptor Isoforms

Biological Activity

Chemical Information

Protocol

순도&문서

References

Calculators

Help & FAQs

Bioz

SL910102

Losartan

Valsartan

Candesartan

Olmesartan

AVE 0991

Olmesartan medoxomil

Azilsartan

CGP-42112

Olmesartan medoxomil (Standard)

Azilsartan medoxomil

PD 123319 ditrifluoroacetate

Eprosartan mesylate

All Angiotensin Receptor Isoforms

Biological Activity

Chemical Information

Protocol

순도&문서

References

Calculators

Help & FAQs

SL910102 Related Classifications

HY-100292 Related Classifications

Bioz