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Cat. No.: HY-157792

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Antidepressant agent 6

Antidepressant agent 6 (S-3a) is a lead compound with potent and sustained antidepressant effects. Antidepressant agent 6 (S-3a) displays high cognitive safety margin.Antidepressant agent 6 (S-3a) antagonizes M1 receptors and elevates BDNF levels, suggesting its potential as an antidepressant for further exploration.

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CAS No.: 3031428-01-7
화학식: C₁₇H₂₀FNO₄
분자량:321.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Antidepressant agent 6 Chemical Structure

CAS No.: 3031428-01-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All mAChR Isoforms :

In Vivo

Antidepressant agent 6 (S-3a) alleviates depressive symptoms in mice and displayes a higher cognitive safety margin than scopolamine^[1].
Antidepressant agent 6 (S-3a) alleviates despair behavior in CRS mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Reserpine-Induced Depression Model in Mice^[1].
Dosage:

25, 100, or 300 μg/kg.
Administration:

Administered intraperitoneally every other day.
Result:

Did not cause changes in total distance during the OFT, suggesting its antidepressant-like effects were independent of locomotor activity.
Could alleviate depression-induced weight loss relative to the untreated model group.

Chemical Information

CAS No. 3031428-01-7
분자량 321.34
화학식 C₁₇H₂₀FNO₄
SMILES

CN1[C@@H]2CC(C[C@H]1[C@@H]3O[C@@H]32)OC([C@@](CO)(C4=CC=CC=C4)F)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Le Wang, et al. Design, Synthesis, and Activity Evaluation of Fluorine-Containing Scopolamine Analogues as Potential Antidepressants. J Med Chem. 2024 Feb 14. [Content Brief]

Calculators

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Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- In Vivo
Chemical Information
순도&문서
References

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Antidepressant agent 6

All mAChR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Antidepressant agent 6 Related Classifications

HY-157792 Related Classifications