CB2R agonist 1
CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role.
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- CAS No.: 1817633-49-0
- 화학식: C22H32N2O
- 분자량:340.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CB2R 0.56 μM (EC50) |
CB2R agonist 1 (Compound 4) (1 μM and 10 μM; 24 h) increases the production of IL-4 and IL-10 anti-inflammatory cytokines and reduces the production of TNF-α, IFN-γ, IL-1β and IL-6 pro-inflammatory cytokines in monocytes and macrophages with concentration-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1817633-49-0
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분자량 340.50
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화학식 C22H32N2O
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SMILES
O=C(C1=C(NCCCCC)C=CC=C1)NC23CC4CC(C3)CC(C2)C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CB2R agonist 1 Related Classifications
HY-152576 Related Classifications
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