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Cat. No.: HY-187119

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CC13401

CC13401 is an aldose reductase (ALR2) inhibitor with an IC₅₀ of 41.41 μM in rats. CC13401 inhibits the NADPH-dependent reduction reaction catalyzed by ALR2. CC13401 can be used in studies on the mechanisms related to the polyol pathway and diabetic complications.

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CAS No.: 158575-73-6
화학식: C₁₇H₁₅NO₄
분자량:297.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CC13401 Chemical Structure

CAS No.: 158575-73-6

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

ALR2

41.41 μM (IC₅₀)

In Vitro

Carbohydrate Metabolism

CC13401 (compound 9) tested as a racemate, specifically inhibits rat lens-derived aldose reductase with an IC₅₀ of 41.41 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 158575-73-6
분자량 297.31
화학식 C₁₇H₁₅NO₄
SMILES

O=C(N1C2=CC=CC=C2C[C@@H]1C(O)=O)OCC3=CC=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Cosconati S, et al. Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening. Journal of medicinal chemistry. 2009 Sep 24;52(18):5578-81. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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