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Cat. No.: HY-169379

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CSI118 TFA

CSI118 TFA (Compound 1) is a Ligand for Target Protein for PROTAC. CSI118 TFA can be used to synthesize CSI86 (HY-169378).

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CAS No.: 3063898-01-8
화학식: C₂₄H₁₉F₁₂N₃O₄
분자량:641.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CSI118 TFA Chemical Structure

CAS No.: 3063898-01-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

CSI118 TFA (Compound 1) is a Ligand for Target Protein for PROTAC. CSI118 TFA can be used to synthesize CSI86 (HY-169378)^[1].

Chemical Information

CAS No. 3063898-01-8
분자량 641.41
화학식 C₂₄H₁₉F₁₂N₃O₄
SMILES

O=C(C(F)(F)F)O.FC(F)(C1=NN(C)C(C2=C(O)C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=C(OCCCN)C=C2)=C1)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Siokatas C, et al. Developing MYC Degraders Bearing the Von Hippel–Lindau Ligand to Target the “Undruggable” MYC[J]. ACS Pharmacology & Translational Science, 2024.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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