Dideoxycytidinene
Based on 1 Customer Validation
Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.36%
- CAS No.: 7481-88-1
- 화학식: C9H11N3O3
- 분자량:209.20
-
보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| ATH-8 cell line | ED50 |
0.3 μM
Compound: 2b
|
Protection of ATH8 cells against the cytopathic effect of HIV.
Protection of ATH8 cells against the cytopathic effect of HIV.
|
[PMID: 3497272] |
| CCRF-CEM | ED50 |
>20 μM
Compound: 1
|
In vitro concentration required to decrease 50% of mitochondrial DNA content in CEM cells
In vitro concentration required to decrease 50% of mitochondrial DNA content in CEM cells
|
[PMID: 8627596] |
| CCRF-CEM | ED50 |
20 μM
Compound: 1
|
In vitro concentration required to inhibit 50% of CEM cell growth
In vitro concentration required to inhibit 50% of CEM cell growth
|
[PMID: 8627596] |
| HepG2 | ED50 |
10 nM
Compound: 1
|
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
|
[PMID: 8627596] |
| HepG2 | ED50 |
8 nM
Compound: 1
|
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
|
[PMID: 8627596] |
| MT2 | ED50 |
1 μM
Compound: 1
|
Concentration required to inhibit 50% of HIV activity in MT-2 cells
Concentration required to inhibit 50% of HIV activity in MT-2 cells
|
[PMID: 8627596] |
| MT4 | ED50 |
0.13 μM
Compound: d4Cyd
|
Effective dose achieving 50% protection of MT-4 cells against the cytopathic effect of HIV
Effective dose achieving 50% protection of MT-4 cells against the cytopathic effect of HIV
|
[PMID: 2342078] |
Chemical Information
-
CAS No. 7481-88-1
-
Appearance Solid
-
분자량 209.20
-
화학식 C9H11N3O3
-
Color White to light yellow
-
SMILES
OC[C@@H]1C=C[C@H](N2C(N=C(N)C=C2)=O)O1
-
Synonyms
2′,3′-Didehydro-2′,3′-dideoxycytidine
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
순도&문서
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dideoxycytidinene Related Classifications
HY-145791 Related Classifications
Powered by Bioz