Eliapixant (Standard)
Eliapixant (Standard) is the analytical standard of Eliapixant (HY-109170). This product is intended for research and analytical applications. Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
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- CAS No.: 1948229-21-7
- 화학식: C22H21F3N4O3S
- 분자량:478.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1948229-21-7
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분자량 478.49
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화학식 C22H21F3N4O3S
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SMILES
C[C@H](C1=CN=C(C(F)(F)F)N=C1)NC(C2=CC(O[C@@H]3CCOC3)=CC(C4=NC=C(S4)C)=C2)=O
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Synonyms
BAY 1817080 (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561. [Content Brief]
[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)