Eperisone
Eperisone ((±)-Eperisone) is an antispasmodic agent and centrally acting muscle relaxant useful in the study of diseases characterized by muscle stiffness and pain. Eperisone acts by relaxing skeletal and vascular smooth muscle, resulting in vasodilation, decreased muscle tone, improved circulation, and inhibition of pain reflexes. Eperisone is also a potent P2X7 receptor antagonist.
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- CAS No.: 64840-90-0
- 화학식: C17H25NO
- 분자량:259.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All P2X Receptor Isoforms
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Biological Activity
제품 설명
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 64840-90-0
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분자량 259.39
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화학식 C17H25NO
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SMILES
O=C(C1=CC=C(CC)C=C1)C(C)CN2CCCCC2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[3]. Bavage S, et al. Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. Pharmacol Rep. 2016 Oct;68(5):903-12. [Content Brief]
[4]. Okada M, et al. Eperisone Hydrochloride, a Muscle Relaxant, Is a Potent P2X7 Receptor Antagonist. Chem Pharm Bull (Tokyo). 2024;72(3):345-348. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)