Evofolin A
Evofolin A is a conjugated benzophenone derivative and monocyclic polyketide that exists in the heartwood of Phellodendron chinense var. glabriusculum, the herb Sida acuta, and the filamentous fungus Aspergillus oryzae. Evofolin A acts as an inducer of quinone reductase activity in cultured hepatoma cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 168146-21-2
- 화학식: C10H12O4
- 분자량:196.20
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
More
Biological Activity
제품 설명
IC50 & Target
[1]|
Microbial Metabolite |
In Vitro
Evofolin A (6 days) production in Aspergillus oryzae requires the ppsA and ppsB genes, while ppsC enhances Evofolin A yield, and ppsD is not involved in Evofolin A biosynthesis[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 168146-21-2
-
분자량 196.20
-
화학식 C10H12O4
-
SMILES
C[C@H](O)C(C1=CC(OC)=C(C=C1)O)=O
-
Structure Classification
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
-
Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)