Indecainide
Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity.
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- CAS No.: 74517-78-5
- 화학식: C20H24N2O
- 분자량:308.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Indecainide (4 mg/kg, p.o.) results in rapid absorption by 15 min[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Dogs[1]
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Dosage:1-5 mg/kg
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Administration:Intravenous injection
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Result:Decreased cardiac contractility.
Chemical Information
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CAS No. 74517-78-5
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분자량 308.42
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화학식 C20H24N2O
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SMILES
O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C
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Synonyms
Ricainide; LY 135837 free base
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61. [Content Brief]
[2]. Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12(6): 691-697. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Indecainide Related Classifications
HY-121306 Related Classifications
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