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Iptocigistat

(Synonyms: Iptocigistatum)

Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase (cGAS) inhibitor. Iptocigistat prevents excessive immune responses. Iptocigistat can be used to study inflammation-related autoimmune diseases.

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CAS No.: 3047739-67-0
화학식: C₁₈H₂₂N₆O₆S
분자량:450.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Iptocigistat Chemical Structure

CAS No.: 3047739-67-0

사이즈

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수량

Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Bioz

Biological Activity

제품 설명

In Vitro

Iptocigistat (Compound 10) inhibits the activity of human guanylate-adenylate cyclase in a cell-free Kinase-Glo assay, with an IC₅₀ ranging from ≥0.005 μM to <0.02 μM^[1].
Iptocigistat inhibits the activity of human guanylate-adenylate synthase in cell-free LCMS assays, with an IC₅₀ of ≥0.005 μM and <0.02 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3047739-67-0
분자량 450.47
화학식 C₁₈H₂₂N₆O₆S
SMILES

O=C1OC(C(NC2=NN=C(N3N=CC=C3C)S2)=O)=CC(NC(COC)COC)=C1OC
Synonyms

Iptocigistatum
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Ramsay Beveridge, et al. Thiadiazole derivatives as inhibitors of cyclic gmp-amp synthase and uses thereof. WO2024137607A1. 2025-06-20

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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