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Cat. No.: HY-156986

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ITH15004

ITH15004 is a CNS-penetrated P2X7 antagonist, used for the study of neurodegenerative diseases.

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CAS No.: 2600675-12-3
화학식: C₁₃H₇Cl₃N₄O
분자량:341.58

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ITH15004 Chemical Structure

CAS No.: 2600675-12-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

ITH15004 is a CNS-penetrated P2X7 antagonist, used for the study of neurodegenerative diseases^[1].

All P2X Receptor Isoforms :

Chemical Information

CAS No. 2600675-12-3
분자량 341.58
화학식 C₁₃H₇Cl₃N₄O
SMILES

O=C(CN1C=NC2=C1N=CN=C2Cl)C3=CC=C(C=C3Cl)Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Francesco Calzaferri, et al. Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. J Med Chem. 2021 Feb 25;64(4):2272-2290. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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ITH15004

High-Throughput Bioactive Compound Library

All P2X Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ITH15004 Related Classifications

HY-156986 Related Classifications