KP-1212
Based on 1 Customer Validation
KP-1212 is a nucleoside. KP-1212 exerts its antiviral effect by mutagenizing the viral genome. KP-1212 inhibits HIV growth.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.07%
- CAS No.: 114522-16-6
- 화학식: C8H14N4O4
- 분자량:230.22
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U373-MAGI | EC50 |
21.6 nM
Compound: KP-1212
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Potentiation of gemcitabine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 5 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of gemcitabine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 5 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
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[PMID: 24120088] |
| U373-MAGI | EC50 |
248 μM
Compound: KP-1212
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Potentiation of deferoxamine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of deferoxamine-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
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[PMID: 24120088] |
| U373-MAGI | EC50 |
52.8 μM
Compound: KP-1212
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Potentiation of resveratrol-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
Potentiation of resveratrol-induced antiviral activity against HIV1 infected in human U373-MAGI cells at 200 uM incubated for 2 hrs prior to viral infection followed by compound washout after 24 hrs measured 72 hrs post-infection by flow cytometry
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[PMID: 24120088] |
Chemical Information
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CAS No. 114522-16-6
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Appearance Solid
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분자량 230.22
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화학식 C8H14N4O4
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Color White to off-white
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SMILES
O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)CN=C(N)N1
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Synonyms
DHDAC; SN-1212
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
H2O : 5 mg/mL (21.72 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.3437 mL | 21.7184 mL | 43.4367 mL | 108.5918 mL |
| 5 mM | 0.8687 mL | 4.3437 mL | 8.6873 mL | 21.7184 mL | |
| 10 mM | 0.4344 mL | 2.1718 mL | 4.3437 mL | 10.8592 mL | |
| 15 mM | 0.2896 mL | 1.4479 mL | 2.8958 mL | 7.2395 mL | |
| 20 mM | 0.2172 mL | 1.0859 mL | 2.1718 mL | 5.4296 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
KP-1212 Related Classifications
HY-106252 Related Classifications
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