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Cat. No.: HY-10143

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LY-2434074

LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC₅₀ <100 nM. LY-2434074 can inhibit amyloid-β (Aβ₄₀ and Aβ₄₂) production. LY-2434074 can be used for the research of neurological disease, such as Alzheimer's disease.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 883446-27-3
화학식: C₂₁H₃₃ClF₂N₂O₄
분자량:450.95

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

LY-2434074 Chemical Structure

CAS No.: 883446-27-3

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 883446-27-3
분자량 450.95
화학식 C₂₁H₃₃ClF₂N₂O₄
SMILES

O[C@H]([C@]1([H])N[C@H]([C@@H](OC1)OCC(C)(C)C)C)[C@@H](NC(C)=O)CC2=CC(F)=CC(F)=C2.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Timothy Barrett Durham, et al. 3- (2-acylamino-1-hydroxyethyl)- morpholine derivatives and their use as bace inhibitors. WO2006034093A2. 2006-03-30

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

LY-2434074

All Beta-secretase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LY-2434074 Related Classifications

HY-10143 Related Classifications