N6-Aminoadenosine
N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 5746-27-0
- 화학식: C10H14N6O4
- 분자량:282.26
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | GI50 |
1.03 μM
Compound: 5
|
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| HeLa | GI50 |
0.52 μM
Compound: 5
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| HT-29 | GI50 |
1.44 μM
Compound: 5
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| K562 | GI50 |
0.61 μM
Compound: 5
|
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| KB | CC50 |
2.26 μM
Compound: 2a
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 17548196] |
| MCF7 | GI50 |
0.35 μM
Compound: 5
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
Chemical Information
-
CAS No. 5746-27-0
-
분자량 282.26
-
화학식 C10H14N6O4
-
SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC=N/C3=N\N)=C3N=C2)O1
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)