Nagilactone C
Based on 1 Customer Validation
Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.
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- Purity: 98%
- CAS No.: 24338-53-2
- 화학식: C19H22O7
- 분자량:362.37
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| AGS | IC50 |
2.3 μM
Compound: 7j
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Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| HeLa | IC50 |
3.3 μM
Compound: 7j
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Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| HepG2 | IC50 |
14 μM
Compound: 7j
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Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| MDA-MB-231 | IC50 |
5 μM
Compound: 7j
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Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| P388 | IC50 |
0.33 μg/mL
Compound: 1
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Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
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[PMID: 1800635] |
| PANC-1 | IC50 |
>40 μM
Compound: 7j
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Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
Chemical Information
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CAS No. 24338-53-2
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Appearance Solid
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분자량 362.37
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화학식 C19H22O7
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Color White to off-white
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SMILES
C[C@@]1(C2=C3)[C@]4([H])[C@]([C@@H](O)[C@@H]5[C@H]1O5)(C(O[C@]4([H])[C@H](O)C2=C(C(C)C)OC3=O)=O)C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
순도&문서
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nagilactone C Related Classifications
HY-N3215 Related Classifications
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