NH2-PEG6-Boc
Based on 1 Customer Validation
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.0%
- CAS No.: 1286281-32-0
- 화학식: C19H39NO8
- 분자량:409.51
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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HY-W019799
Amino-PEG8-Boc -
HY-140193
Amino-PEG4-BocPROTAC Linkers -
HY-42149
NH2-PEG2-C2-BocPROTAC/ADC Linker -
HY-100216
SPDPADC linker -
HY-130200
NH2-PEG8-OHPROTAC Linkers -
HY-W008005
Amino-PEG4-alcohol -
HY-126889
Bis-PEG5-NHS esterADC/PROTAC Linker -
HY-140197
Amino-PEG12-Boc -
HY-W040289
Mal-amido-PEG2-NHS esterADC Linker -
HY-W067489
NH2-PEG1-CH2CH2-BocPROTAC Linker -
HY-W040257
NH2-PEG6-CH2CH2COOH -
HY-129637
NH2-PEG5-OHPROTAC/ADC Linker
All PROTAC Linkers Isoforms
More
Biological Activity
제품 설명
IC50 & Target
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PEGs |
Alkyl/ether |
Non-cleavable Linker |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 1286281-32-0
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Appearance Liquid (Density: 1.056±0.06 g/cm3)
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분자량 409.51
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화학식 C19H39NO8
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCN
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
순도&문서
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Data Sheet (262 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NH2-PEG6-Boc Related Classifications
HY-130486 Related Classifications
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