PDE4-IN-16
Based on 1 publication(s) in Google Scholar
PDE4-IN-16 (compound 27) is a PDE4 inhibitor with an IC50 value of 3.61 μM. PDE4-IN-16 can be used for the research of inflammatory diseases and central nervous system (CNS) disorders involving elevated levels of cytokines.
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- Purity : 98.84%
- CAS No.: 223500-15-0
- 화학식: C13H12F3N3O2
- 분자량:299.25
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PDE4-IN-16
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Biological Activity
제품 설명
IC50 & Target
IC50: 3.61 μM (PDE4)[1].
Chemical Information
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CAS No. 223500-15-0
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Appearance Solid
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분자량 299.25
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화학식 C13H12F3N3O2
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Color Off-white to light brown
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SMILES
O=C(C1=C(C(F)(F)F)N(C2=CC=C(N)C=C2)N=C1)OCC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
용액&용해도
In Vitro:
DMSO : 45 mg/mL (150.38 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3417 mL | 16.7084 mL | 33.4169 mL | 83.5422 mL |
| 5 mM | 0.6683 mL | 3.3417 mL | 6.6834 mL | 16.7084 mL | |
| 10 mM | 0.3342 mL | 1.6708 mL | 3.3417 mL | 8.3542 mL | |
| 15 mM | 0.2228 mL | 1.1139 mL | 2.2278 mL | 5.5695 mL | |
| 20 mM | 0.1671 mL | 0.8354 mL | 1.6708 mL | 4.1771 mL | |
| 25 mM | 0.1337 mL | 0.6683 mL | 1.3367 mL | 3.3417 mL | |
| 30 mM | 0.1114 mL | 0.5569 mL | 1.1139 mL | 2.7847 mL | |
| 40 mM | 0.0835 mL | 0.4177 mL | 0.8354 mL | 2.0886 mL | |
| 50 mM | 0.0668 mL | 0.3342 mL | 0.6683 mL | 1.6708 mL | |
| 60 mM | 0.0557 mL | 0.2785 mL | 0.5569 mL | 1.3924 mL | |
| 80 mM | 0.0418 mL | 0.2089 mL | 0.4177 mL | 1.0443 mL | |
| 100 mM | 0.0334 mL | 0.1671 mL | 0.3342 mL | 0.8354 mL |
PDE4-IN-16 Related Classifications
HY-W186242 Related Classifications
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