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Cat. No.: HY-156032

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PIMPC

PIMPC is a compound with antioxidant and metal-chelating properties. PIMPC is a novel inhibitor of glycogen synthase kinase 3 (GSK-3). PIMPC has potential anti-Alzheimer's disease effect.

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CAS No.: 2250244-44-9
화학식: C₂₁H₁₉N₅O
분자량:357.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PIMPC Chemical Structure

CAS No.: 2250244-44-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PIMPC is a compound with antioxidant and metal-chelating properties. PIMPC is a novel inhibitor of glycogen synthase kinase 3 (GSK-3). PIMPC has potential anti-Alzheimer's disease effect^[1].

All GSK-3 Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
PC-12	IC₅₀	83.18 μM Compound: 9b	Cytotoxicity against rat PC12 cells measured after 24 hrs by MTT assay Cytotoxicity against rat PC12 cells measured after 24 hrs by MTT assay	[PMID: 30772605]
SH-SY5Y	IC₅₀	158.07 μM Compound: 9b	Cytotoxicity against human SH-SY5Y cells measured after 24 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells measured after 24 hrs by MTT assay	[PMID: 30772605]

Chemical Information

CAS No. 2250244-44-9
분자량 357.41
화학식 C₂₁H₁₉N₅O
SMILES

O=C(C1CC1)NC2=NC=CC(/C=N/C3=CC(C4=CC=CC=C4)=CN=C3N)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu D, et al. A quantitative analysis method for a new glycogen synthase kinase-3 inhibitor and its pharmacokinetics in rats. Biomed Chromatogr. 2023 Aug;37(8):e5649. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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PIMPC

All GSK-3 Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PIMPC Related Classifications

HY-156032 Related Classifications