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Cat. No.: HY-106580A

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Plafibride hydrochloride

(Synonyms: ITA 104 hydrochloride)

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor.

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CAS No.: 65285-81-6
화학식: C₁₆H₂₃Cl₂N₃O₄
분자량:392.28

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Plafibride hydrochloride Chemical Structure

CAS No.: 65285-81-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Plafibride hydrochloride (ITA 104 hydrochloride) is an orally active hypolipemic, platelet aggregation inhibitor^[1]^[2].

All Lipocalin Family Isoforms :

Retinol Binding Protein

In Vivo

Plafibride (100 mg/kg, p.o.) hydrochloride shows marked platelet anti-aggregant activity in rabbits^[1].
Plafibride hydrochloride has low toxicity, with LD₅₀s of about 4000 mg/kg (p.o.) in rat, mouse and hamster^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rabbit^[1]
Dosage:

100 mg/kg
Administration:

Oral administration (p.o.)
Result:

Induced platelet aggregation.

Chemical Information

CAS No. 65285-81-6
분자량 392.28
화학식 C₁₆H₂₃Cl₂N₃O₄
SMILES

O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(C=C2)Cl)=O.Cl
Synonyms

ITA 104 hydrochloride
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]

[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- In Vivo
Chemical Information
순도&문서
References

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Plafibride hydrochloride

All Lipocalin Family Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Plafibride hydrochloride Related Classifications

HY-106580A Related Classifications