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Cat. No.: HY-180895

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Y207–5465

Y207–5465 is a potent and highly selective PLK2 inhibitor with an IC₅₀ value of 584.3 nM. Y207–5465 shows only limited anti-cancer activity in HT-29 and HCT-116 cells. Y207–5465 can be used in cancer research.

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CAS No.: 667404-66-2
화학식: C₂₀H₁₆N₄O₃
분자량:360.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Y207–5465 Chemical Structure

CAS No.: 667404-66-2

사이즈

가격

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

TFCP2

63 nM (Ki)

All Polo-like Kinase (PLK) Isoforms :

Chemical Information

CAS No. 667404-66-2
분자량 360.37
화학식 C₂₀H₁₆N₄O₃
SMILES

OC1=CC=CC=C1C2C(C(C3=CC=C(OC)C=C3)=NN4)=C4OC(N)=C2C#N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu YW, et al. Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment. J Chem Inf Model. 2026 Jan 12;66(1):577-590. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Y207–5465

All Polo-like Kinase (PLK) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Y207–5465 Related Classifications

HY-180895 Related Classifications