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Cat. No.: HY-108660R

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PSB-0739 (Standard)

PSB-0739 (Standard) is the analytical standard of PSB-0739 (HY-108660). This product is intended for research and analytical applications. PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a K_i values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect.

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CAS No.: 1052087-90-7
화학식: C₂₆H₁₇N₃Na₂O₈S₂
분자량:609.54

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PSB-0739 (Standard) Chemical Structure

CAS No.: 1052087-90-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1052087-90-7
분자량 609.54
화학식 C₂₆H₁₇N₃Na₂O₈S₂
SMILES

O=S(C(C(N)=C1C2=O)=CC(NC3=CC=C(NC4=CC=CC=C4)C(S(=O)(O[Na])=O)=C3)=C1C(C5=C2C=CC=C5)=O)(O[Na])=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Younis Baqi, et al. High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y₁₂ receptors. J Med Chem. 2009 Jun 25;52(12):3784-93. [Content Brief]

[2]. Kristina Hoffmann, et al. Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y₁₂ receptor. J Pharmacol Exp Ther. 2009 Nov;331(2):648-55. [Content Brief]

[3]. J J Micklewright,et al. P2Y 12 receptor modulation of ADP-evoked intracellular Ca²⁺ signalling in THP-1 human monocytic cells. Br J Pharmacol.2018 Jun;175(12):2483-2491. [Content Brief]

[4]. Gergely Horváth, et al. Central P2Y₁₂ receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents. Neurobiol Dis. 2014 Oct;70(100):162-78. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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