PSB-24000
PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM against human CD73 (Ki= 481 nM at membrane-bound CD73 in triple-negative breast cancer cells). PSB-24000 interferes with CD73's recognition and action on the substrate AMP, and prevents the generation of immunosuppressive and cancer-promoting adenosine from AMP. PSB-24000 is promising for research of cancers.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C20H28ClN5O6P2
- 분자량:531.87
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
분자량 531.87
-
화학식 C20H28ClN5O6P2
-
SMILES
O=P(CP(O)(O)=O)(OCCCCCCN1C=NC2=C(N(CC3=CC=CC=C3)C)N=C(Cl)N=C12)O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)