PSB-24000

PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM against human CD73 (Ki= 481 nM at membrane-bound CD73 in triple-negative breast cancer cells). PSB-24000 interferes with CD73's recognition and action on the substrate AMP, and prevents the generation of immunosuppressive and cancer-promoting adenosine from AMP. PSB-24000 is promising for research of cancers.

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  • 화학식: C20H28ClN5O6P2
  • 분자량:531.87
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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