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Cat. No.: HY-16560B

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(R)-Camptothecin

(Synonyms: (R)-Campathecin; (R)-(+)-Camptothecin; (R)-CPT)

(R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 110351-92-3
화학식: C₂₀H₁₆N₂O₄
분자량:348.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

(R)-Camptothecin Chemical Structure

CAS No.: 110351-92-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

(R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1^[1].

All Topoisomerase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	>30 μM Compound: 5ao	Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells	[PMID: 8410981]

Chemical Information

CAS No. 110351-92-3
분자량 348.35
화학식 C₂₀H₁₆N₂O₄
SMILES

CC[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC=C5C=C4C3)=C2)=O)O
Synonyms

(R)-Campathecin; (R)-(+)-Camptothecin; (R)-CPT
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xiangshu Xiao, et al. Effect of E-Ring Modifications in Camptothecin on Topoisomerase I Inhibition: A Quantum Mechanics Treatment. J Org Chem. 2005 Nov 11;70(23):9584-7. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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(R)-Camptothecin

All Topoisomerase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(R)-Camptothecin Related Classifications

HY-16560B Related Classifications