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Cat. No.: HY-15179

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Ronomilast

Name: Ronomilast
Brand: MedChemExpress
SKU: HY-15179
Availability: PreOrder

(Synonyms: Elbimilast; ELB353)

Ronomilast (Elbimilast; ELB353) is an orally active phosphodiesterase-4 (PDE4) inhibitor with an IC₅₀ of 3 nM. Revamilast can be used for research to inflammation related diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 418794-42-0
화학식: C₂₁H₁₅Cl₂FN₄O₂
분자량:445.27

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Ronomilast Chemical Structure

CAS No.: 418794-42-0

사이즈

가격

재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Clinical Trial
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Ronomilast (Elbimilast; ELB353) is an orally active phosphodiesterase-4 (PDE4) inhibitor with an IC₅₀ of 3 nM. Revamilast can be used for research to inflammation related diseases^[1].

IC₅₀ & Target

^[1]

PDE4

3 nM (IC₅₀)

All Phosphodiesterase (PDE) Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Chemical Information

CAS No. 418794-42-0
분자량 445.27
화학식 C₂₁H₁₅Cl₂FN₄O₂
SMILES

FC1=CC=C(CN2C(N=CC=C3)C3=C(C(C(NC4=C(Cl)C=NC=C4Cl)=O)=O)C2)C=C1
Synonyms

Elbimilast; ELB353
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Peng T, et al. Advances in the development of phosphodiesterase-4 inhibitors. Journal of medicinal chemistry. 2020 Apr 7;63(19):10594-617.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Clinical Trial
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

Ronomilast

All Phosphodiesterase (PDE) Isoforms

Biological Activity

제품 설명

IC50 & Target

Clinical Trial

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Ronomilast Related Classifications

HY-15179 Related Classifications

Bioz

Keywords

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