Saponarin (Standard)
Saponarin (Standard) is the analytical standard of Saponarin (HY-N5083). This product is intended for research and analytical applications. Saponarin is an orally active flavonoid compound. Saponarin can be isolated from Gypsophila trichotoma. Saponarin inhibits ERK/p38, NF-κB and MAPK phosphorylation and activates AMPK. Saponarin reduces IL-1β and COX-2. Saponarin has antioxidant, anti-inflammatory, hepatoprotective, hypoglycemic and hypotensive effects. Saponarin improves sleep disorders.
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- CAS No.: 20310-89-8
- 화학식: C27H30O15
- 분자량:594.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-N5083
SaponarinFlavonoid -
HY-N0803
Myrcene,75% (stabilized with BHT)NF-κB Inhibitor -
HY-N0022
IsoacteosideNatural Product -
HY-N1441
AfzelinFlavonol Glycoside -
HY-N0924
(±)-StylopineAlkaloid -
HY-N0647
SilychristinMCT8 Inhibitor -
HY-N3220
Myricetin 3-O-galactosideXO Inhibitor -
HY-76225
Ammonium glycyrrhizinateAnti-tumor Agent -
HY-131516
Tiopronin-cysteine disulfideMetabolite/Derivative of Tiopronin -
HY-N1441R
Afzelin (Standard)Flavonol Glycoside -
HY-126738
Anacardic acid trieneEster Product -
HY-N0924R
(±)-Stylopine (Standard)Alkaloid
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 20310-89-8
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분자량 594.52
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화학식 C27H30O15
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SMILES
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C([C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)C(O)=C13
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Simeonova R, et al. Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine. 2016 May 15;23(5):483-90. [Content Brief]
[2]. Seo KH, et al. Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 2014 Nov;5(11):3005-13. [Content Brief]
[3]. Seo WD, et al. Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5237-42. [Content Brief]
[4]. Kamiyama M, et al. Flavonoids with potent antioxidant activity found in young green barley leaves. J Agric Food Chem. 2012 Jun 27;60(25):6260-7. [Content Brief]
[5]. Min SY, et al. Anti-Inflammatory and Anti-Allergic Effects of Saponarin and Its Impact on Signaling Pathways of RAW 264.7, RBL-2H3, and HaCaT Cells. Int J Mol Sci. 2021 Aug 5;22(16):8431. [Content Brief]
[6]. Vitcheva V, et al. Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats. Redox Rep. 2011;16(2):56-61. [Content Brief]
[7]. Kim YR, et al. Effect of Hibiscus syriacus Linnaeus extract and its active constituent, saponarin, in animal models of stress-induced sleep disturbances and pentobarbital-induced sleep. Biomed Pharmacother. 2022 Feb;146:112301. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Saponarin (Standard) Related Classifications
HY-N5083R Related Classifications
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