ST80
ST80 is an inhibitor for interaction of OTUD4 and CD73. ST80 decreases CD73 protein level, increases CD73 protein turnover, reduces immune evasion of tumor cells, and thus exhibits antitumor efficacy against immunosuppressive triple-negative breast cancer (TNBC).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3080717-78-5
- 화학식: C26H24FN5O2
- 분자량:457.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
제품 설명
Chemical Information
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CAS No. 3080717-78-5
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분자량 457.50
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화학식 C26H24FN5O2
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SMILES
O=C1N(C2=NN([C@@H](C3=CC=C(F)C=C3)C[C@@H](C4=CC=C(C)C=C4)N5)C5=N2)C([C@@]6([H])CC=CC[C@]61[H])=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Hot Topics
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Topics Process of PD-1/PD-L1-Mediated Tumor Immune Evasion
PD-1/PD-L1-mediated tumor immune evasion is a central mechanism by which tumors suppress antitumor immunity through immune checkpoint signaling.
2026-06-18
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Topics Escape Route Built by TGF-β Signaling
Escape route built by TGF-β signaling refers to the immunosuppressive and stromal remodeling program through which tumors avoid immune elimination and reduce response to cancer immunotherapy.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ST80 Related Classifications
HY-161774 Related Classifications
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