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Cat. No.: HY-N15314

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Syringolin A

Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae. Syringolin A exhibits anti-proliferative activity against a variety of cancer cells (IC₅₀ for SK-N-SH, LAN-1, SKOV3 is 20-25 µM), induces apoptosis in SK-N-SH through upregulation of p53 expression and downregulation of Akt/PKB proteins.

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CAS No.: 212115-96-3
화학식: C₂₄H₃₉N₅O₆
분자량:493.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Syringolin A Chemical Structure

CAS No.: 212115-96-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Akt Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MM1.S	IC₅₀	8.5 μM Compound: 1	Cytotoxicity against human MM1.S cells Cytotoxicity against human MM1.S cells	[PMID: 38704960]
MM1.S	IC₅₀	8500 nM Compound: 1	Cytotoxicity against human MM1S cells Cytotoxicity against human MM1S cells	[PMID: 26231162]

Chemical Information

CAS No. 212115-96-3
분자량 493.60
화학식 C₂₄H₃₉N₅O₆
SMILES

CC(C)[C@@H](C(O)=O)NC(N[C@H](C(N[C@@H]1C(N[C@@H](C(C)C)/C=C/C(NCC/C=C/1)=O)=O)=O)C(C)C)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Pseudomonas syringae pv.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Coleman CS, et al., Syringolin A, a new plant elicitor from the phytopathogenic bacterium Pseudomonas syringae pv. syringae, inhibits the proliferation of neuroblastoma and ovarian cancer cells and induces apoptosis. Cell Prolif. 2006 Dec;39(6):599-609. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Syringolin A

All Akt Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Syringolin A Related Classifications

HY-N15314 Related Classifications