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Cat. No.: HY-120022

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THPP-2

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1393750-01-0
화학식: C₂₇H₂₇N₇O
분자량:465.56

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

THPP-2 Chemical Structure

CAS No.: 1393750-01-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia^[1].

IC₅₀ & Target

^[1]

PDE10A

94 nM (Ki)

All Phosphodiesterase (PDE) Isoforms :

Chemical Information

CAS No. 1393750-01-0
분자량 465.56
화학식 C₂₇H₂₇N₇O
SMILES

O=C(NC=1C=CC=CC1)N2CC=3C(=NC(=NC3CC2)C=4C=CN=CC4)N(C)CCC5=NC=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012;22(18):5903-5908. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Biological Activity
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Chemical Information
순도&문서
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THPP-2

All Phosphodiesterase (PDE) Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

THPP-2 Related Classifications

HY-120022 Related Classifications

Bioz

Keywords

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