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Cat. No.: HY-123685

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UCD74A (hydrochloride)

UCD74A hydrochloride is a 5-substituted Amiloride (HY-B0285) analog and urokinase-type plasminogen activator (uPA) inhibitor with an IC₅₀ of 110 μM. UCD74A hydrochloride modulates plasminogen activation cascades linked to extracellular matrix remodeling. UCD74A hydrochloride can be used for the research of tumor metastasis.

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CAS No.: 1345838-99-4
화학식: C₈H₁₁Cl₂N₇O₃
분자량:324.12

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

UCD74A (hydrochloride) Chemical Structure

CAS No.: 1345838-99-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

UCD74A (compound 18) hydrochloride inhibits high molecular weight urokinase-type plasminogen activator (HMW-uPA) with an IC₅₀ of 110 μM in an in vitro enzyme assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1345838-99-4
분자량 324.12
화학식 C₈H₁₁Cl₂N₇O₃
SMILES

O=C(CNC1=NC(N)=C(N=C1Cl)C(NC(N)=N)=O)O.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Matthews H, et al. Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA). Bioorg Med Chem Lett. 2011;21(22):6760-6766. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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