VH4127
VH4127 is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127, bearing non-natural amino acid residues, specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C40H71N15O9S4
- 분자량:1034.35
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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hLDLR 18 nM (Kd) |
Chemical Information
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분자량 1034.35
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화학식 C40H71N15O9S4
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Sequence
Pr-cyclo[{d-Cys}-Met-Thz-Arg-Leu-Arg-Gly-Pen]-NH2
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Sequence Shortening
Pr-cyclo[{d-Cys}-M-Thz-RLRG-Pen]-NH2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Xue Yang, et al. Preparation and In Vitro Validation of a Cucurbit[7]uril-Peptide Conjugate Targeting the LDL Receptor. J Med Chem. 2023 Jul 13;66(13):8844-8857. [Content Brief]
[2]. Angélina Acier, et al. LDL receptor-peptide conjugate as in vivo tool for specific targeting of pancreatic ductal adenocarcinoma. Commun Biol. 2021 Aug 19;4(1):987. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VH4127 Related Classifications
HY-P10697 Related Classifications
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