KRAS G12C inhibitor 17
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 82, has an IC50 of 5 nM.
For research use only. We do not sell to patients.
- CAS No.: 2349393-04-8
- Formula: C24H20ClF2N3O3
- Molecular Weight:471.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
KRas G12C 5 nM (IC50) |
Chemical Information
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CAS No. 2349393-04-8
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Molecular Weight 471.88
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Formula C24H20ClF2N3O3
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SMILES
FC1=CC=CC(O)=C1C2=C(F)C(N=CC3=C4N5[C@H](CN(C(C=C)=O)[C@H](C)C5)CO3)=C4C=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRAS G12C inhibitor 17 Related Classifications
HY-125875 Related Classifications
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