KRAS G12C inhibitor 68
KRAS G12C inhibitor 68 (compound I-063) is a KRAS G12C inhibitor with an IC50 of 7 nM. KRAS G12C inhibitor 68 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3034851-27-6
- Formula: C35H44F2N6O3
- Molecular Weight:634.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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KRas G12C 7 nM (IC50) |
Chemical Information
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CAS No. 3034851-27-6
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Molecular Weight 634.76
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Formula C35H44F2N6O3
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SMILES
FC(C1=C2C(N3[C@](CC=C2)([H])[C@H](N4CCN(CC4)C(C=C)=O)C3)=CC(N5[C@@H](C[C@@H](C6=C(C7(COC7)OC)N=CC=C6C)CC5)C)=N1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)