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Referencia número: HY-159611

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KRAS G12C inhibitor 68

KRAS G12C inhibitor 68 (compound I-063) is a KRAS G12C inhibitor with an IC₅₀ of 7 nM. KRAS G12C inhibitor 68 has anti-tumor activity.

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No. CAS: 3034851-27-6
Fòrmula: C₃₅H₄₄F₂N₆O₃
Peso molecular:634.76

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

KRAS G12C inhibitor 68 Chemical Structure

No. CAS: 3034851-27-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- IC₅₀ & Target
Chemical Information
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Actividad biológica

Descripciòn

KRAS G12C inhibitor 68 (compound I-063) is a KRAS G12C inhibitor with an IC₅₀ of 7 nM. KRAS G12C inhibitor 68 has anti-tumor activity^[1].

IC₅₀ & Target

KRas G12C

7 nM (IC₅₀)

Ver todos los productos específicos de isoformas Ras :

Chemical Information

No. CAS 3034851-27-6
Peso molecular 634.76
Fòrmula C₃₅H₄₄F₂N₆O₃
SMILES

FC(C1=C2C(N3[C@](CC=C2)([H])[C@H](N4CCN(CC4)C(C=C)=O)C3)=CC(N5[C@@H](C[C@@H](C6=C(C7(COC7)OC)N=CC=C6C)CC5)C)=N1)F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Brian A. Lanman, et al. Tethered heterocyclic inhibitors of kras g12c mutant proteins and uses thereof. WO2024076670A3.2024-05-30.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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KRAS G12C inhibitor 68

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Actividad biológica
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- IC₅₀ & Target
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KRAS G12C inhibitor 68

Ver todos los productos específicos de isoformas Ras

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

KRAS G12C inhibitor 68 Related Classifications

HY-159611 Related Classifications