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Cat. No.: HY-169311

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KRAS inhibitor-37

KRAS inhibitor-37 is a KRAS inhibitor. KRAS inhibitor-37 inhibits the activity of KRAS^G12C, KRAS^G12D, and KRAS^G12V receptors. KRAS inhibitor-37 can be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 3058573-95-5
Formula: C₃₂H₃₃ClFN₇O₃
Molecular Weight:618.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

KRAS inhibitor-37 Chemical Structure

CAS No.: 3058573-95-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

KRAS inhibitor-37 is a KRAS inhibitor. KRAS inhibitor-37 inhibits the activity of KRAS^G12C, KRAS^G12D, and KRAS^G12V receptors. KRAS inhibitor-37 can be used in cancer research^[1].

IC₅₀ & Target

^[1]

KRas G12C

KRas G12D

KRas G12V

All Ras Isoforms :

In Vitro

KRAS inhibitor-37 (Compound 2) inhibits the activity of KRAS^G12C, KRAS^G12D, and KRAS^G12V receptors^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 3058573-95-5
Molecular Weight 618.10
Formula C₃₂H₃₃ClFN₇O₃
SMILES

C=C1CN2CCC[C@]2(C1)COC3=NC4=C5C(OC[C@@H]6COCCCN6C5=N3)=NC(C7=C8C=NNC8=CC(Cl)=C7C9CC9)=C4F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Burke BJ, et al, De‑Forest JC, et al. [Patent title not shown in snippet]. International Patent Application WO 2024/209339 A1. October 10, 2024.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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