L-Glutamic γ-monohydroxamate
Based on 1 Customer Validation
L-Glutamic γ-monohydroxamate is an antitumor agent, inhibits cell proliferation. L-Glutamic γ-monohydroxamate selectively inhibits the uptake of L-histidine into microvascular endothelial cell. L-Glutamic γ-monohydroxamate, as a vanadium ligand, activates glucose uptake and metabolism, thus decreases the blood glucose levels in vivo.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 1955-67-5
- Formula: C5H10N2O4
- Molecular Weight:162.14
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1955-67-5
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Appearance Solid
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Molecular Weight 162.14
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Formula C5H10N2O4
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 83.33 mg/mL (513.94 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Vila J, et al. In vitro and in vivo anti-tumor activity of L-glutamic acid gamma-monohydroxamate against L1210 leukemia and B16 melanoma. Int J Cancer. 1990 Apr 15;45(4):737-43. [Content Brief]
[2]. Sakurai E, et al. Stereoselective transport of histidine in rat lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1192-7. [Content Brief]
[3]. Goldwaser I, et al. L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo. J Biol Chem. 1999 Sep 10;274(37):26617-24. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.1675 mL | 30.8375 mL | 61.6751 mL | 154.1877 mL |
| 5 mM | 1.2335 mL | 6.1675 mL | 12.3350 mL | 30.8375 mL | |
| 10 mM | 0.6168 mL | 3.0838 mL | 6.1675 mL | 15.4188 mL | |
| 15 mM | 0.4112 mL | 2.0558 mL | 4.1117 mL | 10.2792 mL | |
| 20 mM | 0.3084 mL | 1.5419 mL | 3.0838 mL | 7.7094 mL | |
| 25 mM | 0.2467 mL | 1.2335 mL | 2.4670 mL | 6.1675 mL | |
| 30 mM | 0.2056 mL | 1.0279 mL | 2.0558 mL | 5.1396 mL | |
| 40 mM | 0.1542 mL | 0.7709 mL | 1.5419 mL | 3.8547 mL | |
| 50 mM | 0.1234 mL | 0.6168 mL | 1.2335 mL | 3.0838 mL | |
| 60 mM | 0.1028 mL | 0.5140 mL | 1.0279 mL | 2.5698 mL | |
| 80 mM | 0.0771 mL | 0.3855 mL | 0.7709 mL | 1.9273 mL | |
| 100 mM | 0.0617 mL | 0.3084 mL | 0.6168 mL | 1.5419 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Glutamic γ-monohydroxamate Related Classifications
HY-137874 Related Classifications
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