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Art. -Nr.: HY-171368

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L-Histidine buffer,Sterile

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L-Histidine buffer, Sterile is a commonly used antibody storage buffer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.0%

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Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

L-Histidine buffer,Sterile Chemical Structure

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Beschreibung

L-Histidine buffer, Sterile is a commonly used antibody storage buffer.

In Vitro

The core of L-Histidine buffer, Sterile, is L-histidine, an essential basic amino acid for the human body. As a buffer, L-histidine has unique advantages: 1. Excellent buffering capacity: Its imidazole group on the side chain has a pKa value of approximately 6.0, giving it extremely strong buffering capacity within the physiologically relevant pH range of 5.5-6.5. 2. Multiple stabilizing functions: In addition to maintaining pH stability, histidine can also act as a stabilizer, antioxidant, and lyophilization protectant for proteins (especially monoclonal antibodies). It can interact directly with antibody proteins through various complex mechanisms, helping them maintain structural integrity and functional activity during storage and transportation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.