LDHA/PDKs-IN-1
LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases.
For research use only. We do not sell to patients.
- CAS No.: 2490699-40-4
- Formula: C19H21FN2O4
- Molecular Weight:360.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | EC50 |
13.2 μM
Compound: 20e
|
Anticancer activity against human A549 assessed as cell growth inhibition measured after 72 hrs by MTT assay
Anticancer activity against human A549 assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 32688200] |
Chemical Information
-
CAS No. 2490699-40-4
-
Molecular Weight 360.38
-
Formula C19H21FN2O4
-
SMILES
CC1=C(C(C=CO1)=O)OCCN2CCN(CC2)C(C3=CC=C(C=C3)F)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LDHA/PDKs-IN-1 Related Classifications
HY-146977 Related Classifications
Powered by Bioz