Irinotecan liposome is a liposome-encapsulated form of Irinotecan hydrochlorid (HY-16562A) (a topoisomerase I inhibitor). Compared with Irinotecan, Irinotecan liposome enhances antitumor activity, reduces drug release rate, and avoids neutropenia.
Anionic Liposomes (DOPG, 10mM) is a Phosphatidylglycerol (PG)-based-100% DOPG formulation. Anionic Liposomes (DOPG, 10mM) can be used for drug delivery and lipid-protein interactions.
Cas12a mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Cas12a mRNA. Cas12a mRNA encodes the Cas12a protein, where Cas12a is an RNA-guided endonuclease, a core component of gene editing tools.
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
mCherry mRNA (N1-Me-Pseudo UTP)-LNP is a lipid nanoparticle (LNP) encapsulating mCherry mRNA (N1-Me-Pseudo UTP). mCherry mRNA (N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression, cell viability, in vivo imaging, and other detection methods. mCherry is a red fluorescent protein derived from mushroom coral and is widely used in biotechnology as a red fluorescent dye tracer.
Human IL2 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL2 mRNA. Human IL2 mRNA encapsulates human interleukin 2 (IL2) protein, which belongs to the interleukin 2 (IL2) cytokine subfamily. IL2 is produced by activated CD4+ and CD8+ T lymphocytes and is essential for the proliferation of T cells and B lymphocytes.
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
Human IL4 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL4 mRNA. Human IL4 mRNA encapsulates human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells that regulates various T and B cell responses, including cell proliferation, survival, and gene expression.
Human IGF1 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human IGF1 mRNA. Human IGF1 mRNA encapsulates human insulin-like growth factor 1 (IGF1) protein, which is involved in mediating growth and development.
Liposomal Amphotericin B (Amphotericin B liposome) is a liposomal formulation of Amphotericin B (HY-B0221) that can cross the blood-brain barrier. Liposomal Amphotericin B binds to fungal cell walls and releases Amphotericin B to bind Ergosterol (HY-N0181), inducing pore formation, ion leakage, and fungal cell death. Liposomal Amphotericin B exhibits fungicidal activity against a broad spectrum of fungal pathogens, also shows activity against Leishmania, and the liposomal formulation has lower acute and chronic toxicity as well as a lower risk of fungal resistance.
Decitabine-Cisplatin Liposome is a delivery system that encapsulates Decitabine (HY-A0004) and Cisplatin (HY-17394) within tiny liposomes. The liposomes act as a protective layer, enhancing the absorption and bioavailability of both Decitabine and Cisplatin. The combination of Decitabine and Cisplatin synergistically induces Sox2 DNA demethylation and promotes Sox2 gene expression, making it a useful tool for gastric cancer research.
