mRNA-LNP
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Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency.
eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability.
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2.
Cas12a mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Cas12a mRNA. Cas12a mRNA encodes the Cas12a protein, where Cas12a is an RNA-guided endonuclease, a core component of gene editing tools.
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
mCherry mRNA (N1-Me-Pseudo UTP)-LNP is a lipid nanoparticle (LNP) encapsulating mCherry mRNA (N1-Me-Pseudo UTP). mCherry mRNA (N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression, cell viability, in vivo imaging, and other detection methods. mCherry is a red fluorescent protein derived from mushroom coral and is widely used in biotechnology as a red fluorescent dye tracer.
Human IL2 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL2 mRNA. Human IL2 mRNA encapsulates human interleukin 2 (IL2) protein, which belongs to the interleukin 2 (IL2) cytokine subfamily. IL2 is produced by activated CD4+ and CD8+ T lymphocytes and is essential for the proliferation of T cells and B lymphocytes.
Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)-LNP is a lipid nanoparticle (LNP) encapsulating Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP). Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP) encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and green fluorescent protein (GFP), which can be used for genome engineering experiments. N1-Methylpseudo-UTP can reduce the immunogenicity of the generated mRNA.
Human IL4 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating Human IL4 mRNA. Human IL4 mRNA encapsulates human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells that regulates various T and B cell responses, including cell proliferation, survival, and gene expression.
Human IGF1 mRNA-LNP is a lipid nanoparticle (LNP) encapsulating human IGF1 mRNA. Human IGF1 mRNA encapsulates human insulin-like growth factor 1 (IGF1) protein, which is involved in mediating growth and development.
Decitabine-Cisplatin Liposome is a delivery system that encapsulates Decitabine (HY-A0004) and Cisplatin (HY-17394) within tiny liposomes. The liposomes act as a protective layer, enhancing the absorption and bioavailability of both Decitabine and Cisplatin. The combination of Decitabine and Cisplatin synergistically induces Sox2 DNA demethylation and promotes Sox2 gene expression, making it a useful tool for gastric cancer research.
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