LSD1-IN-49 hydrochloride
LSD1-IN-49 hydrochloride (Compound (±) 1) is an irreversible LSD1/KDM1A inhibitor with an IC50 of 29 nM against hLSD1. LSD1-IN-49 hydrochloride irreversibly inhibits the enzymatic activity of LSD1 by forming an adduct with flavin adenine dinucleotide (FAD) in the binding pocket of LSD1. LSD1-IN-49 hydrochloride is applicable to research related to schizophrenia, autism spectrum disorder and Huntington's disease.
For research use only. We do not sell to patients.
- CAS No.: 1422534-06-2
- Formula: C26H27ClN2O
- Molecular Weight:418.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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LSD1 29 (hLSD1) nM (IC50) |
LSD1-IN-49 hydrochloride irreversibly inhibits the activity of recombinant human LSD1 enzyme, with an IC50 of 29 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1422534-06-2
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Molecular Weight 418.96
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Formula C26H27ClN2O
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C=C3)=CC=C3[C@H](C4)[C@@H]4NCC5CC5.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LSD1-IN-49 hydrochloride Related Classifications
HY-186116A Related Classifications
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