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Cat. No.: HY-149731

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M1/M2/M4 muscarinic agonist 2

M1/M2/M4 muscarinic agonist 2 (compound 43) is a muscarinic mAChR M1/M2/M4 agonist with EC₅₀s of 30 nM, 200 nM and 6.2 nM, respectively.

For research use only. We do not sell to patients.

Formula: C₂₃H₃₂N₂O₃
Molecular Weight:384.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

M1/M2/M4 muscarinic agonist 2 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

M1/M2/M4 muscarinic agonist 2 (compound 43) is a muscarinic mAChR M1/M2/M4 agonist with EC₅₀s of 30 nM, 200 nM and 6.2 nM, respectively^[1].

IC₅₀ & Target

EC50: 30 nM (M1 muscarinic receptor), 200 nM (M2 muscarinic receptor), 6.2 nM (M4 muscarinic receptor)^[1]

All mAChR Isoforms :

Chemical Information

Molecular Weight 384.51
Formula C₂₃H₃₂N₂O₃
SMILES

O=C(C1COC1)N(C2)CC2(CC3)CC3N(CC4)CCC4C5=CC=CC=C5OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thomson C G et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists[J]. ACS Medicinal Chemistry Letters, 2023.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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