Malic acid disodium salt
Based on 5 publication(s) in Google Scholar
Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance.
For research use only. We do not sell to patients.
- Purity: 99.04%
- CAS No.: 676-46-0
- Formula: C4H4Na2O5
- Molecular Weight:178.05
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Storage:
RT, stored under nitrogen, away from moisture.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Malic acid disodium salt
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Biological Activity
Sodium DL-Malate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 676-46-0
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Appearance Solid
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Molecular Weight 178.05
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Formula C4H4Na2O5
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Color White to off-white
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SMILES
O=C(CC(C(O[Na])=O)O)O[Na]
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Synonyms
Hydroxybutanedioic acid disodium salt; E 296 disodium salt
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, stored under nitrogen, away from moisture
In solvent -80°C 1 year -20°C 6 months
Publications (5)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Cell Death Dis
Lactate transmission from hypoxic tumor cells promotes macrophage senescence and M2 polarization via the DNMT1-NHE7 axis to accelerate endometrial cancer progression. [Abstract]2026 Jan 30;17(1):185. PMID: 41617670 -
Food Chem
Discovery of novel ascorbic acid derivatives and other metabolites in fruit of Rosa roxburghii Tratt through untargeted metabolomics and feature-based molecular networking. [Abstract]2023 Mar 30;405(Pt A):134807. PMID: 36370576 -
Cell Signal
Testosterone disrupts trophoblast function and immune homeostasis via PTGER4/cAMP/RAP1 and ANXA1-FPR1 signaling in PCOS-complicated preeclampsia. [Abstract]2026 Oct:146:112672. PMID: 42285193 -
Hum Cell
Exosomal miR-145-5p impairs neoadjuvant chemotherapy by suppressing TFRC-mediated macrophage iron uptake and driving M2 polarization in esophageal cancer. [Abstract]2025 Dec 24;39(1):27. PMID: 41444464
Solvent & Solubility
H2O : ≥ 100 mg/mL (561.64 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.6164 mL | 28.0820 mL | 56.1640 mL | 140.4100 mL |
| 5 mM | 1.1233 mL | 5.6164 mL | 11.2328 mL | 28.0820 mL | |
| 10 mM | 0.5616 mL | 2.8082 mL | 5.6164 mL | 14.0410 mL | |
| 15 mM | 0.3744 mL | 1.8721 mL | 3.7443 mL | 9.3607 mL | |
| 20 mM | 0.2808 mL | 1.4041 mL | 2.8082 mL | 7.0205 mL | |
| 25 mM | 0.2247 mL | 1.1233 mL | 2.2466 mL | 5.6164 mL | |
| 30 mM | 0.1872 mL | 0.9361 mL | 1.8721 mL | 4.6803 mL | |
| 40 mM | 0.1404 mL | 0.7020 mL | 1.4041 mL | 3.5102 mL | |
| 50 mM | 0.1123 mL | 0.5616 mL | 1.1233 mL | 2.8082 mL | |
| 60 mM | 0.0936 mL | 0.4680 mL | 0.9361 mL | 2.3402 mL | |
| 80 mM | 0.0702 mL | 0.3510 mL | 0.7020 mL | 1.7551 mL | |
| 100 mM | 0.0562 mL | 0.2808 mL | 0.5616 mL | 1.4041 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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