Metamifop
Based on 1 Customer Validation
Metamifop is a post-emergence lipid synthesis inhibitor herbicide, with an IC50 of 41.1 nM against the carboxyltransferase (CT) domain of chloroplast acetyl-CoA carboxylase (ACCase) in barnyard grass (Echinochloa crus-galli). Metamifop inhibits the activity of the CT domain, thereby blocking fatty acid biosynthesis.
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- CAS. Nr.: 256412-89-2
- Formel: C23H18ClFN2O4
- Molecular Weight:440.86
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
Metamifop potently inhibits ACCase activity in Echinochloa crus-galli with an IC50 of 41.1 nM[1].
Metamifop (3 ns) binds to the dimer interface active site of the Echinochloa crus-galli CT domain via π-π interactions and protonation-dependent hydrogen bonds, with a unique binding region compared to other ACCase inhibitors, and undergoes a conformational shift in the binding site during MD simulations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 256412-89-2
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Appearance Solid
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Molecular Weight 440.86
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Formel C23H18ClFN2O4
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SMILES
O=C(N(C=1C=CC=CC1F)C)C(OC2=CC=C(OC3=NC=4C=CC(Cl)=CC4O3)C=C2)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (538 KB)
- English - EN (538 KB)
- Français - FR (538 KB)
- Deutsch - DE (538 KB)
- Norwegian - NO (538 KB)
- Español - ES (538 KB)
- Swedish - SV (538 KB)
- Italian - IT (538 KB)
- Korean - KR (538 KB)
- Portuguese - PT (538 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Metamifop Related Classifications
HY-113947 Related Classifications
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