Methyl 3-O-methylgallate
Based on 2 publication(s) in Google Scholar
Methyl 3-O-methylgallate (M3OMG) possesses antioxidant effect and can protect neuronal cells from oxidative damage.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 3934-86-9
- Formula: C9H10O5
- Molecular Weight:198.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Methyl 3-O-methylgallate
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Fifty male Wistar rats (8-12 , 7-days old, 200-250 g)[1].
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Dosage:10 and 20 mg/kg.
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Administration:I.P. for 1 week.
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Result:Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.
Chemical Information
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CAS No. 3934-86-9
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Appearance Solid
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Molecular Weight 198.17
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Formula C9H10O5
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Color Off-white to yellow
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SMILES
COC1=CC(C(OC)=O)=CC(O)=C1O
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Synonyms
M3OMG
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
Characterization of two O-methyltransferases involved in the biosynthesis of O-methylated catechins in tea plant. [Abstract]2023 Aug 21;14(1):5075. PMID: 37604798 -
Food Chem
Tannase-catalysed gallic acid release for clean-label inhibition of green tea auto-oxidative browning. [Abstract]2025 Dec 26:503:147775. PMID: 41475257
Solvent & Solubility
DMSO : 100 mg/mL (504.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (12.62 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (12.62 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.0462 mL | 25.2309 mL | 50.4617 mL | 126.1543 mL |
| 5 mM | 1.0092 mL | 5.0462 mL | 10.0923 mL | 25.2309 mL | |
| 10 mM | 0.5046 mL | 2.5231 mL | 5.0462 mL | 12.6154 mL | |
| 15 mM | 0.3364 mL | 1.6821 mL | 3.3641 mL | 8.4103 mL | |
| 20 mM | 0.2523 mL | 1.2615 mL | 2.5231 mL | 6.3077 mL | |
| 25 mM | 0.2018 mL | 1.0092 mL | 2.0185 mL | 5.0462 mL | |
| 30 mM | 0.1682 mL | 0.8410 mL | 1.6821 mL | 4.2051 mL | |
| 40 mM | 0.1262 mL | 0.6308 mL | 1.2615 mL | 3.1539 mL | |
| 50 mM | 0.1009 mL | 0.5046 mL | 1.0092 mL | 2.5231 mL | |
| 60 mM | 0.0841 mL | 0.4205 mL | 0.8410 mL | 2.1026 mL | |
| 80 mM | 0.0631 mL | 0.3154 mL | 0.6308 mL | 1.5769 mL | |
| 100 mM | 0.0505 mL | 0.2523 mL | 0.5046 mL | 1.2615 mL |
Methyl 3-O-methylgallate Related Classifications
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