Milacemide hydrochloride
Milacemide hydrochloride (CP 1552 S), a glycinamide derivative, is an orally active MAO-B inhibitor with anticonvulsant activity. Milacemide hydrochloride reduces the levels of dihydroxyphenylacetic acid and homovanilic acid, but increases the levels of dopamine and serotonin in the caudate nucleus. Milacemide hydrochloride is promising for research of Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 76990-85-7
- Formula: C7H17ClN2O
- Molecular Weight:180.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 76990-85-7
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Molecular Weight 180.68
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Formula C7H17ClN2O
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SMILES
O=C(N)CNCCCCC.Cl
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Synonyms
CP 1552 S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Janssens de Varebeke P, et al. Milacemide, the selective substrate and enzyme-activated specific inhibitor of monoamine oxidase B, increases dopamine but not serotonin in caudate nucleus of rhesus monkey. Neurochem Int. 1990;17(2):325-9. [Content Brief]
[2]. Colombo M, et al. MAO activity, metabolism and anticonvulsant activity of milacemide in rats and mice. J Neural Transm Suppl. 1990;32:123-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)