(-)-(S)-Cibenzoline-d4
(-)-(S)-Cibenzoline-d4 (Escibenzoline-d4) is deuterium labeled (-)-(S)-Cibenzoline. (-)-(S)-Cibenzoline (Escibenzoline), a S(+)-enantiomer of Cibenzoline, is an antiarrhythmic agent.
For research use only. We do not sell to patients.
- Formula: C18H14D4N2
- Molecular Weight:266.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 103419-18-7
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Molecular Weight 266.37
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Formula C18H14D4N2
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SMILES
[2H]C1([2H])C([2H])([2H])N=C([C@@H]2C(C3=CC=CC=C3)(C4=CC=CC=C4)C2)N1
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Synonyms
Escibenzoline-d4; (-)-(S)-Cifenline-d4; (-)-(S)-Ro 22-7796-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. T Niwa, et al. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Drug Metab Dispos. 2000 Sep;28(9):1128-34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)