MNA 279
MNA 279 (X 910279) is an orally active, immunosuppressive malononitrilamide and A 771726 derivative. MNA 279 suppresses IgM and IgG antibody production. MNA 279 prevents the development of systemic lupus erythematosus (SLE)-like disease in mice. MNA 279 prolongs skin xenograft survival in a mouse-to-rat model.
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- CAS. Nr.: 185915-32-6
- Formel: C14H11N3O2
- Molecular Weight:253.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 185915-32-6
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Molecular Weight 253.26
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Formel C14H11N3O2
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SMILES
N#CC1=CC=C(NC(C(C(C2CC2)=O)C#N)=O)C=C1
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Synonyms
X 910279; HMR-279; FK-779
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Schorlemmer HU, et al. Prevention of the development of murine systemic lupus erythematosus (SLE)-like diseases by the malononitrilamides MNA 279 and MNA 715. Inflamm Res. 1997 Aug;46 Suppl 2:S167-8. [Content Brief]
[2]. Schorlemmer HU, et al. The new immunosuppressive malononitrilamide MNA 279 prolongs skin xenograft survival in a mouse-to-rat model. Transplant Proc. 1997 Dec;29(8):3497-500. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MNA 279 Related Classifications
HY-129442 Related Classifications
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