mp-dLAE-PABC-MMAE
Based on 1 Customer Validation
mp-dLAE-PABC-MMAE is a agent-linker conjugate for ADC. mp-dLAE-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (HY-15162). mp-dLAE-PABC-MMAE can be used to synthesis antibody-drug conjugates (ADCs).
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- Pureté: 98.31%
- CAS No.: 2625616-44-4
- Formule: C68H102N10O17
- Masse moléculaire:1331.59
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
Description
Chemical Information
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CAS No. 2625616-44-4
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Appearance Solid
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Masse moléculaire 1331.59
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Formule C68H102N10O17
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Color White to off-white
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SMILES
O=C(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N1[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C2=CC=CC=C2)C)=O)C)CCC1)=O)OC)[C@@H](C)CC)C)=O)=O)OCC3=CC=C(NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](CC(C)C)NC(CCN4C(C=CC4=O)=O)=O)=O)=O)=O)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (75.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7510 mL | 3.7549 mL | 7.5098 mL | 18.7745 mL |
| 5 mM | 0.1502 mL | 0.7510 mL | 1.5020 mL | 3.7549 mL | |
| 10 mM | 0.0751 mL | 0.3755 mL | 0.7510 mL | 1.8775 mL | |
| 15 mM | 0.0501 mL | 0.2503 mL | 0.5007 mL | 1.2516 mL | |
| 20 mM | 0.0375 mL | 0.1877 mL | 0.3755 mL | 0.9387 mL | |
| 25 mM | 0.0300 mL | 0.1502 mL | 0.3004 mL | 0.7510 mL | |
| 30 mM | 0.0250 mL | 0.1252 mL | 0.2503 mL | 0.6258 mL | |
| 40 mM | 0.0188 mL | 0.0939 mL | 0.1877 mL | 0.4694 mL | |
| 50 mM | 0.0150 mL | 0.0751 mL | 0.1502 mL | 0.3755 mL | |
| 60 mM | 0.0125 mL | 0.0626 mL | 0.1252 mL | 0.3129 mL |