mp-dLAE-PABC-MMAE
Based on 1 Customer Validation
mp-dLAE-PABC-MMAE is a agent-linker conjugate for ADC. mp-dLAE-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (HY-15162). mp-dLAE-PABC-MMAE can be used to synthesis antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.31%
- CAS No.: 2625616-44-4
- Formula: C68H102N10O17
- Molecular Weight:1331.59
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 2625616-44-4
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Appearance Solid
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Molecular Weight 1331.59
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Formula C68H102N10O17
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Color White to off-white
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SMILES
O=C(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N1[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C2=CC=CC=C2)C)=O)C)CCC1)=O)OC)[C@@H](C)CC)C)=O)=O)OCC3=CC=C(NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](CC(C)C)NC(CCN4C(C=CC4=O)=O)=O)=O)=O)=O)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (75.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7510 mL | 3.7549 mL | 7.5098 mL | 18.7745 mL |
| 5 mM | 0.1502 mL | 0.7510 mL | 1.5020 mL | 3.7549 mL | |
| 10 mM | 0.0751 mL | 0.3755 mL | 0.7510 mL | 1.8775 mL | |
| 15 mM | 0.0501 mL | 0.2503 mL | 0.5007 mL | 1.2516 mL | |
| 20 mM | 0.0375 mL | 0.1877 mL | 0.3755 mL | 0.9387 mL | |
| 25 mM | 0.0300 mL | 0.1502 mL | 0.3004 mL | 0.7510 mL | |
| 30 mM | 0.0250 mL | 0.1252 mL | 0.2503 mL | 0.6258 mL | |
| 40 mM | 0.0188 mL | 0.0939 mL | 0.1877 mL | 0.4694 mL | |
| 50 mM | 0.0150 mL | 0.0751 mL | 0.1502 mL | 0.3755 mL | |
| 60 mM | 0.0125 mL | 0.0626 mL | 0.1252 mL | 0.3129 mL |